Vales of Anduin
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The Vales of Anduin was the collective name for the large valley of the Anduin, specifically the part east of the Misty Mountains. It is where the Gladden River meets the Anduin and form the Gladden Fields.
In the First Age, the Teleri who were too afraid to cross the Misty Mountains stopped there. They became the Nandor and their leader was Lenwe. Later they left the Vales for the west or became the Elves of Mirkwood or the Galadhrim.
Sometime during the Third Age the Hobbits migrated to the Vales of Anduin and it is their first known location when they left for the west and begun their Wandering Days. When Angmar threatened Eriador, some of the Stoors would return to the east and settled in the Gladden Fields.
The Vales were a fair and fertile land but in the later years they were affected by the shadow of Dol Guldur.